Endogenous factors - Dyshidrosis
In the past, it was believed that eczema manifesting with pruritic vesicles on the palms, soles and in the interdigital areas was due to sweat gland dysfunction or sweat retention – thus the term “dyshidrosis”. This has been disproved, although hyperhidrosis exists in many of these patients. Dyshidrotic hand and foot eczema has been ascribed to several etiologic factors (Link zu Dyshidrotic hand and foot eczema). A number of patients do not exhibit one of these factors, though, falling into the “idiopathic” group. In these patients, an inherited predisposition is made responsible for the manifested dyshidrotic eczema.